BDBM50081906 6-Ethyl-5-(3-heptyloxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL135935

SMILES CCCCCCCOc1cccc(Cc2c(N)nc(N)nc2CC)c1

InChI Key InChIKey=PXQRPGCLAGOHNS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50081906   

TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081906(6-Ethyl-5-(3-heptyloxy-benzyl)-pyrimidine-2,4-diam...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081906(6-Ethyl-5-(3-heptyloxy-benzyl)-pyrimidine-2,4-diam...)
Affinity DataKi:  48nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Leishmania major.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081906(6-Ethyl-5-(3-heptyloxy-benzyl)-pyrimidine-2,4-diam...)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081906(6-Ethyl-5-(3-heptyloxy-benzyl)-pyrimidine-2,4-diam...)
Affinity DataKi:  710nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Trypanosoma cruzi.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed