BDBM50081916 5-(3-Pentyloxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL137305

SMILES CCCCCOc1cccc(Cc2cnc(N)nc2N)c1

InChI Key InChIKey=JBHNLHXAYAJKPQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50081916   

TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081916(5-(3-Pentyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081916(5-(3-Pentyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  140nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Leishmania major.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081916(5-(3-Pentyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  210nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Trypanosoma cruzi.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081916(5-(3-Pentyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed