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BDBM50082155 4-Hydroxyamino-N-[3-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-ylmethyl)-phenyl]-benzamide::CHEMBL108677

SMILES: Cc1csc2nc(Cc3cccc(NC(=O)c4ccc(NO)cc4)c3)oc(=O)c12

InChI Key: InChIKey=BKDITHGGNIFOAK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50082155
PNG
(4-Hydroxyamino-N-[3-(5-methyl-4-oxo-4H-thieno[2,3-...)
Show SMILES Cc1csc2nc(Cc3cccc(NC(=O)c4ccc(NO)cc4)c3)oc(=O)c12
Show InChI InChI=1S/C21H17N3O4S/c1-12-11-29-20-18(12)21(26)28-17(23-20)10-13-3-2-4-16(9-13)22-19(25)14-5-7-15(24-27)8-6-14/h2-9,11,24,27H,10H2,1H3,(H,22,25)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 61n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (hCMV) protease


Bioorg Med Chem Lett 9: 3137-42 (1999)


Article DOI: 10.1016/s0960-894x(99)00539-9
BindingDB Entry DOI: 10.7270/Q20V8D98
More data for this
Ligand-Target Pair