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BDBM50082162 2-[4-(3-Amino-benzoyl)-benzyl]-5-methyl-thieno[2,3-d][1,3]oxazin-4-one::CHEMBL326888

SMILES: Cc1csc2nc(Cc3ccc(cc3)C(=O)c3cccc(N)c3)oc(=O)c12

InChI Key: InChIKey=LRYYINHQRCGQMC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082162   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50082162
PNG
(2-[4-(3-Amino-benzoyl)-benzyl]-5-methyl-thieno[2,3...)
Show SMILES Cc1csc2nc(Cc3ccc(cc3)C(=O)c3cccc(N)c3)oc(=O)c12
Show InChI InChI=1S/C21H16N2O3S/c1-12-11-27-20-18(12)21(25)26-17(23-20)9-13-5-7-14(8-6-13)19(24)15-3-2-4-16(22)10-15/h2-8,10-11H,9,22H2,1H3
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MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Cytomegalovirus (hCMV) protease


Bioorg Med Chem Lett 9: 3137-42 (1999)


Article DOI: 10.1016/s0960-894x(99)00539-9
BindingDB Entry DOI: 10.7270/Q20V8D98
More data for this
Ligand-Target Pair