BDBM50082392 CHEMBL324631::PIPERIDINE BASED ANALOGUE OF COCAINE (STRUCTURAL MIX)::piperidine based analogue of cocaine
SMILES CN1CC[C@@H]([C@H](CCCN2CCS[Re]3(=O)SCCN3C(=O)C2)C1)c1ccc(Cl)cc1
InChI Key InChIKey=WUTFONXEMABJOL-FOKFTXDMSA-K
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50082392
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]-mazindol as a radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 888nMAssay Description:Inhibition of monoamine [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 888nMAssay Description:Inhibition of monoamine [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair