BDBM50082392 CHEMBL324631::PIPERIDINE BASED ANALOGUE OF COCAINE (STRUCTURAL MIX)::piperidine based analogue of cocaine

SMILES CN1CC[C@@H]([C@H](CCCN2CCS[Re]3(=O)SCCN3C(=O)C2)C1)c1ccc(Cl)cc1

InChI Key InChIKey=WUTFONXEMABJOL-FOKFTXDMSA-K

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50082392   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  43nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  43nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  110nMAssay Description:Inhibition of monoamine [3H]-DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  112nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]-mazindol as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  888nMAssay Description:Inhibition of monoamine [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  888nMAssay Description:Inhibition of monoamine [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082392(CHEMBL324631 | PIPERIDINE BASED ANALOGUE OF COCAIN...)
Affinity DataKi:  2.03E+3nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed