BDBM50082436 CHEMBL138273::[2-(4-Benzooxazol-2-yl-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid

SMILES OC(=O)C(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(cc1)-c1nc2ccccc2o1

InChI Key InChIKey=CLKXWRSURRSEKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082436   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082436([2-(4-Benzooxazol-2-yl-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082436([2-(4-Benzooxazol-2-yl-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed