BDBM50082449 2-(4,5-Dibromo-thiophene-2-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::CHEMBL140426

SMILES ONC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1cc(Br)c(Br)s1

InChI Key InChIKey=YOFBHXUFTFPQDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082449   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082449(2-(4,5-Dibromo-thiophene-2-sulfonyl)-1,2,3,4-tetra...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082449(2-(4,5-Dibromo-thiophene-2-sulfonyl)-1,2,3,4-tetra...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed