BDBM50082470 5-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-4-methoxy-thiophene-3-carboxylic acid methyl ester::CHEMBL140305

SMILES COC(=O)c1csc(c1OC)S(=O)(=O)N1Cc2ccccc2CC1C(=O)NO

InChI Key InChIKey=QESMDPOTHYLJHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082470   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082470(5-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082470(5-(3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinoline-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed