BDBM50082474 CHEMBL138613::{(S)-1-[3-Hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester

SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2cc(NC(=O)[C@H](C)NC(=O)OC(C)(C)C)ccc2CC1C(=O)NO

InChI Key InChIKey=PNICWAPKRSLYIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082474   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082474({(S)-1-[3-Hydroxycarbamoyl-2-(4-methoxy-benzenesul...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082474({(S)-1-[3-Hydroxycarbamoyl-2-(4-methoxy-benzenesul...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed