BDBM50082485 2-[4-(Benzoylamino-methyl)-thiophene-2-sulfonyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::CHEMBL343326

SMILES ONC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1cc(CNC(=O)c2ccccc2)cs1

InChI Key InChIKey=IMRWXXAPWNPDGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082485   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082485(2-[4-(Benzoylamino-methyl)-thiophene-2-sulfonyl]-1...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082485(2-[4-(Benzoylamino-methyl)-thiophene-2-sulfonyl]-1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed