BDBM50082512 CHEMBL138264::[2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid

SMILES OC(=O)C(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(s1)-c1ccon1

InChI Key InChIKey=SRXJKOWUSBFUNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082512   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082512([2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3,4-...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082512([2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3,4-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed