BDBM50082535 (S)-2,2-Dimethyl-4-(4-phenoxy-benzenesulfonyl)-[1,4]thiazepane-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-phenoxyphenylsulfonyl)-1,4-thiazepane-3-carboxamide::CHEMBL140569

SMILES CC1(C)SCCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PZPOCZWOYXDPDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082535   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082535((S)-2,2-Dimethyl-4-(4-phenoxy-benzenesulfonyl)-[1,...)
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082535((S)-2,2-Dimethyl-4-(4-phenoxy-benzenesulfonyl)-[1,...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082535((S)-2,2-Dimethyl-4-(4-phenoxy-benzenesulfonyl)-[1,...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082535((S)-2,2-Dimethyl-4-(4-phenoxy-benzenesulfonyl)-[1,...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed