BDBM50082813 4-(3,4-Difluoro-phenyl)-3-{[2-(4-methoxycarbonyl-4-phenyl-piperidin-1-yl)-ethylcarbamoyl]-methyl}-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL144938

SMILES COC(=O)C1C(N(CC(=O)NCCN2CCC(CC2)(C(=O)OC)c2ccccc2)C(=O)N=C1C)c1ccc(F)c(F)c1

InChI Key InChIKey=VSNJJGGZANSWQT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082813   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082813(4-(3,4-Difluoro-phenyl)-3-{[2-(4-methoxycarbonyl-4...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity against alpha-1A adrenergic receptor of human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082813(4-(3,4-Difluoro-phenyl)-3-{[2-(4-methoxycarbonyl-4...)
Affinity DataKi:  610nMAssay Description:In vitro binding affinity against alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082813(4-(3,4-Difluoro-phenyl)-3-{[2-(4-methoxycarbonyl-4...)
Affinity DataKi:  1.05E+3nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed