BDBM50082829 4-(3,4-Difluoro-phenyl)-3-[3-(4-methoxy-4-phenyl-piperidin-1-yl)-propylcarbamoyl]-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL144965

SMILES COC(=O)C1=C(C)NC(=O)N(C1c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(OC)c1ccccc1

InChI Key InChIKey=FUAZJQZXKXKCSP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082829   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082829(4-(3,4-Difluoro-phenyl)-3-[3-(4-methoxy-4-phenyl-p...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity against alpha-1A adrenergic receptor of human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082829(4-(3,4-Difluoro-phenyl)-3-[3-(4-methoxy-4-phenyl-p...)
Affinity DataKi:  250nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082829(4-(3,4-Difluoro-phenyl)-3-[3-(4-methoxy-4-phenyl-p...)
Affinity DataKi:  370nMAssay Description:In vitro binding affinity against alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed