BDBM50082849 4-(3,4-Difluoro-phenyl)-3-{3-[4-(4-methoxy-2-methyl-phenyl)-piperazin-1-yl]-propylcarbamoyl}-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL145756

SMILES COC(=O)C1=C(C)NC(=O)N(C1c1ccc(F)c(F)c1)C(=O)NCCCN1CCN(CC1)c1ccc(OC)cc1C

InChI Key InChIKey=VYEWPTHCXXZXSS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082849   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082849(4-(3,4-Difluoro-phenyl)-3-{3-[4-(4-methoxy-2-methy...)
Affinity DataKi:  16nMAssay Description:In vitro binding affinity against Alpha-1A adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082849(4-(3,4-Difluoro-phenyl)-3-{3-[4-(4-methoxy-2-methy...)
Affinity DataKi:  510nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082849(4-(3,4-Difluoro-phenyl)-3-{3-[4-(4-methoxy-2-methy...)
Affinity DataKi:  610nMAssay Description:In vitro binding affinity against Alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed