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BDBM50083523 (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine::CHEMBL281622::CP-339818::[1-Benzyl-1H-quinolin-(4E)-ylidene]-pentyl-amine

SMILES: CCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12

InChI Key: InChIKey=MMGAVKCAGQCFHS-LSDHQDQOSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083523   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.3


(Mus musculus)
BDBM50083523
PNG
((1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine | CH...)
Show SMILES CCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C21H24N2/c1-2-3-9-15-22-20-14-16-23(17-18-10-5-4-6-11-18)21-13-8-7-12-19(20)21/h4-8,10-14,16H,2-3,9,15,17H2,1H3/b22-20+
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 230n/an/an/an/an/an/a



University of Kiel

Curated by ChEMBL


Assay Description
Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uM


J Med Chem 44: 1249-56 (2001)


Article DOI: 10.1021/jm001007u
BindingDB Entry DOI: 10.7270/Q2TH8KZV
More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50083523
PNG
((1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine | CH...)
Show SMILES CCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C21H24N2/c1-2-3-9-15-22-20-14-16-23(17-18-10-5-4-6-11-18)21-13-8-7-12-19(20)21/h4-8,10-14,16H,2-3,9,15,17H2,1H3/b22-20+
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Displacement of [125I]- ChTX from human T cell voltage-gated potassium channel subunit Kv1.3


Bioorg Med Chem Lett 9: 3267-72 (2000)


Article DOI: 10.1016/s0960-894x(99)00601-0
BindingDB Entry DOI: 10.7270/Q2765DJW
More data for this
Ligand-Target Pair