BDBM50083955 (6,7-Dimethoxy-quinazolin-4-yl)-(3-methylsulfanyl-phenyl)-amine::4-[3-METHYLSULFANYLANILINO]-6,7-DIMETHOXYQUINAZOLINE::CHEMBL29641

SMILES COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)SC

InChI Key InChIKey=FUSDVOSGGMBSMK-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083955   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50083955(4-[3-METHYLSULFANYLANILINO]-6,7-DIMETHOXYQUINAZOLI...)
Affinity DataIC50: 127nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed