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BDBM50084136 (R)-1-Amino-indan-1,5-dicarboxylic acid::CHEMBL358882

SMILES: N[C@@]1(CCc2cc(ccc12)C(O)=O)C(O)=O

InChI Key: InChIKey=LSTPKMWNRWCNLS-LLVKDONJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50084136
PNG
((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)
Show SMILES N[C@@]1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universit¿a di Perugia

Curated by ChEMBL


Assay Description
Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)


J Med Chem 42: 5390-401 (2000)


Article DOI: 10.1021/jm990353c
BindingDB Entry DOI: 10.7270/Q2ZG6RGS
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50084136
PNG
((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)
Show SMILES N[C@@]1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)/t11-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.14E+5n/an/an/an/an/an/a



Universit¿a di Perugia

Curated by ChEMBL


Assay Description
Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.


J Med Chem 42: 5390-401 (2000)


Article DOI: 10.1021/jm990353c
BindingDB Entry DOI: 10.7270/Q2ZG6RGS
More data for this
Ligand-Target Pair