BDBM50084137 2-Methyl-6-(phenylethynyl)pyridine::2-Methyl-6-phenylethynyl-pyridine::2-Methyl-6-phenylethynyl-pyridine(MPEP)::2-methyl-6-(2-phenylethynyl)pyridine::2-methyl-6-(phenyl-ethynyl)pyridine::2-methyl-6-(phenylethynyl)-pyridine::6-methyl-2-(2-phenylethynyl)pyridine::CHEMBL1788108::CHEMBL66654::MPEP::US10618900, No. MPEP::[3H]-2-methyl-6-(phenylethynyl)-pyridine

SMILES: Cc1cccc(n1)C#Cc1ccccc1

InChI Key: InChIKey=NEWKHUASLBMWRE-UHFFFAOYSA-N

Data: 42 KI  42 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 85 hits for monomerid = 50084137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Mouse)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50084137 (2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair