BDBM50084244 CHEMBL542267::N,N-Diethyl-4-[(3-methoxy-phenyl)-piperidin-4-ylidene-methyl]-benzamide; hydrochloride

SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7]-[#6]-[#6]-1)\c1cccc(-[#8]-[#6])c1

InChI Key InChIKey=UWERJSHTOGBZDV-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084244   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084244(CHEMBL542267 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity to Opioid receptor delta 1 in rat brain membranes by [3H]DADLE (Tyr-D-Ala-Gly-Phe-D-Leu) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084244(CHEMBL542267 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Affinity DataKi:  1.00E+4nMAssay Description:In vitro radioligand binding assay, for inhibition of [3H]DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 in rat brain membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084244(CHEMBL542267 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Affinity DataKi:  1.00E+4nMAssay Description:In vitro radioligand binding assay, for inhibition of [3H]U-69593 binding to Opioid receptor kappa 1, in guinea pig brain membranes, at highest conce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084244(CHEMBL542267 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Affinity DataIC50:  2.77E+4nMAssay Description:Agonist activity using strips of guinea pig ileum longitudinal muscle myenteric plexus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084244(CHEMBL542267 | N,N-Diethyl-4-[(3-methoxy-phenyl)-p...)
Affinity DataIC50:  125nMAssay Description:Agonist activity using electrically induced smooth muscle contraction of mouse vas deferens.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed