BDBM50084257 CHEMBL3425958

SMILES Cn1cncc1CC(=O)Nc1cncc(c1)-c1cccc2[nH]ccc12

InChI Key InChIKey=DEWPKMJIGINBLO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084257   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084257(CHEMBL3425958)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084257(CHEMBL3425958)
Affinity DataKd: <2.00E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed