BDBM50084258 CHEMBL3425959

SMILES FC(F)(F)CN1CCC(CC1)NC(=O)c1ccc(Oc2ccccc2)nc1

InChI Key InChIKey=REUYZXSZARPXHX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084258   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084258(CHEMBL3425959)
Affinity DataIC50:  31nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084258(CHEMBL3425959)
Affinity DataKd:  60nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed