BDBM50084337 CHEMBL67078::[1-(2-Benzhydryloxy-ethyl)-piperidin-3-ylmethyl]-(3-phenyl-propyl)-amine

SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1

InChI Key InChIKey=FDTFUBJUWHYSGU-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084337   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataKi:  41nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataKi:  320nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50:  105nMAssay Description:Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50:  770nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50084337(CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50:  48nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed