BDBM50084419 Andrographolide::CHEBI:65408
SMILES [H][C@]12CCC(=C)[C@@H](C\C=C3/[C@H](O)COC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO
InChI Key InChIKey=BOJKULTULYSRAS-OTESTREVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50084419
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of TNF-alpha-stimulated NF-kappaB p50 (unknown origin) expressed in HEK293 cells preincubated for 4 hrs followed by TNF-alpha challenge me...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau
Curated by ChEMBL
University Of Macau
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau
Curated by ChEMBL
University Of Macau
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human AD293 cells incubated with NF-kappaB for 16 hrs followed by compound addition measured a...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau
Curated by ChEMBL
University Of Macau
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of C-terminal His 6 tagged SARS CoV-2 main protease transfected in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau
Curated by ChEMBL
University Of Macau
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human HK2 expressed in Escherichia coli BL21(DE3) using glucose as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at Gal4 DBD-fused human FXR LBD expressed in human HepG2 cells after 8 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau
Curated by ChEMBL
University Of Macau
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...More data for this Ligand-Target Pair