BDBM50084436 CHEMBL3426693

SMILES Cc1cc(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)ccc1NC(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1

InChI Key InChIKey=GDJRFZAXEHZNNO-BHVANESWSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084436   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50084436(CHEMBL3426693)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50084436(CHEMBL3426693)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed