BDBM50084464 CHEMBL3426891

SMILES: CN1CCN(CC1)c2ccc(cc2)Nc3ncc(c(n3)NC[C@H]4CCCO4)Cl

InChI Key: InChIKey=MMJSYUQCKWEFRW-UHFFFAOYSA-N

Data: 10 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50084464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase ROS (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	438	n/a	n/a	n/a	n/a	n/a	n/a
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Activated CDC42 kinase 1 (Human)	BDBM50084464 (CHEMBL3426891) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
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