BDBM50084744 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid benzyl ester::CHEMBL332134

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1

InChI Key InChIKey=DNGGPLKVDUPXFN-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084744   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  1.90nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  18nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  232nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084744(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed