BDBM50084893 (S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethylamino)propanoic acid::3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-propionic acid::CHEMBL146936

SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NCP(O)(O)=O

InChI Key InChIKey=CRUVAUSVWLATAE-ZDUSSCGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084893   

TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50084893((S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethyla...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084893((S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethyla...)
Affinity DataIC50:  22nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084893((S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethyla...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084893((S)-3-(dibenzo[b,d]furan-3-yl)-2-(phosphonomethyla...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed