BDBM50084905 CHEMBL147964::{1-[2-Dibenzofuran-3-yl-1-(1H-tetrazol-5-yl)-ethylamino]-3-naphthalen-1-yl-propyl}-phosphonic acid

SMILES OP(O)(=O)C(CCc1cccc2ccccc12)N[C@@H](Cc1ccc2c(c1)oc1ccccc21)c1nnn[nH]1

InChI Key InChIKey=TUPJIGTXAYPCTF-BXXZMZEQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084905   

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  2.60nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  2.60nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed