BDBM50084959 11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo-[2,3-f]indole-3,4'-piperidine](SB-224289)::4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl-1'-methylspiro[3,5,6,7-tetrahydro-2H-furo[2,3-f]indole-3,4'-(hexahydropyridine)]-5-ylmethanone::CHEMBL281350::SB-224289::US20240166639, Example SB9::[2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-yl]-[3-(1-methyl-piperidine)-2,3,6,7-tetrahydro-1-oxa-5-aza-s-indacen-5-yl]-methanone

SMILES: CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1

InChI Key: InChIKey=ATQMRMGXINTJHV-UHFFFAOYSA-N

Data: 41 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 45 hits for monomerid = 50084959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Rat)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium-dependent serotonin transporter (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		5.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Guinea pig)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Pig)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Mouse)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1F (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1E (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1E (Human)	BDBM50084959 (4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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