BDBM50085024 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine.2HCl::CHEMBL52399

SMILES C[C@H]1C2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1

InChI Key InChIKey=STNPURITMRUHGJ-PEYLTSRESA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50085024   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity was determined against Opioid receptor kappa 1 obtained from guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity was determined against Opioid receptor mu 1 obtained from guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  12nMAssay Description:Binding affinity was determined against Opioid receptor delta 1 obtained from guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  110nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  506nMAssay Description:Binding affinity was determined against Opioid receptor kappa 1 obtained from guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  506nMAssay Description:Binding affinity was determined against Opioid receptor kappa 1 obtained from guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  780nMAssay Description:Binding affinity was determined against Opioid receptor mu 1 obtained from guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  780nMAssay Description:Binding affinity was determined against Opioid receptor mu 1 obtained from guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  920nMAssay Description:Binding affinity was determined against Opioid receptor delta 1 obtained from guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50085024((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  920nMAssay Description:Binding affinity was determined against Opioid receptor delta 1 obtained from guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed