BDBM50085260 CHEMBL26424::Tesmilifene::[2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine

SMILES CCN(CC)CCOc1ccc(Cc2ccccc2)cc1

InChI Key InChIKey=NFIXBCVWIPOYCD-UHFFFAOYSA-N

Data  2 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085260   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085260(CHEMBL26424 | Tesmilifene | [2-(4-Benzyl-phenoxy)-...)
Show SMILES CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C19H25NO/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17/h5-13H,3-4,14-16H2,1-2H3
Affinity DataIC50: 400nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085260(CHEMBL26424 | Tesmilifene | [2-(4-Benzyl-phenoxy)-...)
Show SMILES CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
Show InChI InChI=1S/C19H25NO/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17/h5-13H,3-4,14-16H2,1-2H3
Affinity DataIC50: 160nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair