BDBM50085457 CHEMBL89533::{(S)-6-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-2,2-dimethyl-7-oxo-azepan-1-yl}-acetic acid

SMILES CC1(C)CCC[C@H](NC(=O)[C@@H](CN(O)C=O)Cc2ccccc2)C(=O)N1CC(O)=O

InChI Key InChIKey=PWWQUDACQHLHAI-SJORKVTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085457   

TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085457(CHEMBL89533 | {(S)-6-[(R)-2-Benzyl-3-(formyl-hydro...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085457(CHEMBL89533 | {(S)-6-[(R)-2-Benzyl-3-(formyl-hydro...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed