BDBM50086039 CHEMBL10350::[2-(4-Bromo-2-fluoro-benzyl)-6-fluoro-1,3-dioxo-1,2,3,4-tetrahydro-isoquinolin-4-yl]-acetic acid

SMILES OC(=O)CC1C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2ccc(F)cc12

InChI Key InChIKey=AUUUWTFZKUNERC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086039   

TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086039([2-(4-Bromo-2-fluoro-benzyl)-6-fluoro-1,3-dioxo-1,...)
Affinity DataIC50: 227nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed