BDBM50086366 3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-(3-phenyl-propyl)-propionamide::CHEMBL347750

SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCCc1ccccc1

InChI Key InChIKey=AHTQSMPGKJEFNT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086366   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086366(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed