BDBM50086570 CHEMBL435191::Edotecarin::NB-506 Analogue

SMILES: OCC(CO)NN1C(=O)c2c(C1=O)c1c3ccc(O)cc3n([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1c1[nH]c3cc(O)ccc3c21

InChI Key: InChIKey=QMVPQBFHUJZJCS-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Human)	BDBM50086570 (Edotecarin | NB-506 Analogue | CHEMBL435191) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50086570 (Edotecarin | NB-506 Analogue | CHEMBL435191) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50086570 (Edotecarin | NB-506 Analogue | CHEMBL435191) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Human)	BDBM50086570 (Edotecarin | NB-506 Analogue | CHEMBL435191) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair