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BDBM50086864 CHEMBL3426367

SMILES: NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(\C=C\c3ccc(F)cc3)nc2c1

InChI Key: InChIKey=DUELRCOKXDCVQL-KPKJPENVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086864   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50086864
PNG
(CHEMBL3426367)
Show SMILES NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(\C=C\c3ccc(F)cc3)nc2c1
Show InChI InChI=1S/C21H16FN3O2S/c22-16-9-5-14(6-10-16)7-12-21-24-18-11-8-15(13-19(18)25-21)17-3-1-2-4-20(17)28(23,26)27/h1-13H,(H,24,25)(H2,23,26,27)/b12-7+
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MMDB

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Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx preincubated for 5 m...


J Med Chem 58: 3859-74 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00132
BindingDB Entry DOI: 10.7270/Q2154JS3
More data for this
Ligand-Target Pair