BDBM50087074 CHEMBL32079::N-{4-(3-Chloro-4-fluoro-phenylamino)-7-[2-(4-hydroxy-butoxy)-ethoxy]-quinazolin-6-yl}-acrylamide

SMILES OCCCCOCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

InChI Key InChIKey=HVRIYPDAXABTLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087074   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087074(N-{4-(3-Chloro-4-fluoro-phenylamino)-7-[2-(4-hydro...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed