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BDBM50087095 1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl)-propyl]-hydroxy-phosphinoyl}-ethyl-ammonium

SMILES: C[C@@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccc(Br)cc1)C(=O)N[C@@H](C)C(O)=O

InChI Key: InChIKey=WRVVJFLQCNNQSS-JBLDHEPKSA-O

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087095   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50087095
PNG
(1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl...)
Show SMILES C[C@@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccc(Br)cc1)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C15H22BrN2O5P/c1-9(15(20)21)18-14(19)12(8-24(22,23)10(2)17)7-11-3-5-13(16)6-4-11/h3-6,9-10,12H,7-8,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/p+1/t9-,10-,12+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.90n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.


J Med Chem 43: 1398-408 (2001)


Article DOI: 10.1021/jm990483l
BindingDB Entry DOI: 10.7270/Q2TQ627J
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50087095
PNG
(1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl...)
Show SMILES C[C@@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccc(Br)cc1)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C15H22BrN2O5P/c1-9(15(20)21)18-14(19)12(8-24(22,23)10(2)17)7-11-3-5-13(16)6-4-11/h3-6,9-10,12H,7-8,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/p+1/t9-,10-,12+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.90n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.


J Med Chem 43: 1398-408 (2001)


Article DOI: 10.1021/jm990483l
BindingDB Entry DOI: 10.7270/Q2TQ627J
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50087095
PNG
(1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl...)
Show SMILES C[C@@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccc(Br)cc1)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C15H22BrN2O5P/c1-9(15(20)21)18-14(19)12(8-24(22,23)10(2)17)7-11-3-5-13(16)6-4-11/h3-6,9-10,12H,7-8,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/p+1/t9-,10-,12+/m0/s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.40E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
inhibitory activity on angiotensin I converting enzyme (ACE) using cbz-Phe-His-Leu as substrate.


J Med Chem 43: 1398-408 (2001)


Article DOI: 10.1021/jm990483l
BindingDB Entry DOI: 10.7270/Q2TQ627J
More data for this
Ligand-Target Pair