BDBM50087129 CHEMBL3426633

SMILES COC(=O)c1ccc(F)c(NC(=O)c2cccc(c2)-c2cc(ccc2CN)C(=O)Nc2ccncc2F)c1

InChI Key InChIKey=OZKJLTGMZXEHHT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087129   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50087129(CHEMBL3426633)
Affinity DataIC50:  46nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50087129(CHEMBL3426633)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair