BDBM50087486 7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-3-phenyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione::CHEMBL43909

SMILES COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5c6nc(cnc6sc5c4=O)-c4ccccc4)C[C@@H]3CCc12

InChI Key InChIKey=QQGYNGUUZMLKBV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087486   

TargetAlpha-1A adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50087486(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  3.91nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50087486(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  19.8nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1D adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50087486(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  120nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1B adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed