BDBM50087535 3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazole-4-carboxylic acid [5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-amide::CHEMBL160115

SMILES COCc1onc(c1C(=O)Nc1ccc(cn1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N

InChI Key InChIKey=JXIMXKWLTVKHDN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087535   

TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed