BDBM50088066 CHEMBL439931::N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N-benzenesulfonyl)ureido-benzenesulfonyl)-amino]-acetamide

SMILES ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=UGBFTDFVLBACAS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088066   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088066(CHEMBL439931 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088066(CHEMBL439931 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088066(CHEMBL439931 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088066(CHEMBL439931 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088066(CHEMBL439931 | N-Hydroxy-2-[(4-nitro-benzyl)-(4-(N...)
Affinity DataKi:  61nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed