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BDBM50088155 4-Imidazol-1-yl-6-(4-methyl-piperazin-1-yl)-pyrimidine::CHEMBL56384

SMILES: CN1CCN(CC1)c1cc(ncn1)-n1ccnc1

InChI Key: InChIKey=IYZHTMUYJMWCCH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50088155
PNG
(4-Imidazol-1-yl-6-(4-methyl-piperazin-1-yl)-pyrimi...)
Show SMILES CN1CCN(CC1)c1cc(ncn1)-n1ccnc1
Show InChI InChI=1S/C12H16N6/c1-16-4-6-17(7-5-16)11-8-12(15-9-14-11)18-3-2-13-10-18/h2-3,8-10H,4-7H2,1H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Jagiellonian University

Curated by ChEMBL


Assay Description
Affinity at 5-hydroxytryptamine 2A receptor of the rat brain cortex was assessed on the basis of their ability to displace [3H]-ketanserin


J Med Chem 43: 1901-9 (2000)


Article DOI: 10.1021/jm9911332
BindingDB Entry DOI: 10.7270/Q2QF8S3H
More data for this
Ligand-Target Pair