BDBM50088213 (2S,4R)-4-allyl glutamate::2-Allyl-4-amino-pentanedioic acid(LY310214)::CHEMBL62057::LY-310214

SMILES N[C@@H](C[C@@H](CC=C)C(O)=O)C(O)=O

InChI Key InChIKey=APFSBOCBNKHACW-RITPCOANSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088213   

TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataKi:  56nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataKi:  1.84E+3nMAssay Description:compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-kainate as radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at iGluR6 L439C mutant expressed in human HEK293 cells assessed as increase in intracellular Ca2+ levels by FURA-2-M staining based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataEC50:  4.40E+3nMAssay Description:Effective concentration of the compound required for evoking response in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataEC50:  8.30E+3nMAssay Description:Effective concentration against human GluR6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed