BDBM50088375 1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methyl-amino]-1-oxa-spiro[4.5]dec-7-yl}-pyrrolidinium

SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1[NH+]1CCCC1)C(=O)C1C(=C1c1ccccc1)c1ccccc1

InChI Key InChIKey=DVBJTNONUUBBIZ-QRQMUESOSA-O

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088375   

TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi:  0.640nMAssay Description:Inhibition of [3H]- U-69593 binding in cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi:  0.640nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataEC50:  9.60nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article