BDBM50088401 2-(4-Methoxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL302940

SMILES COc1ccc(cc1)N1C(=O)c2ccc(cc2C1=O)C(=O)NCC(O)CN1CCN(CC1)c1ccccc1OC(C)C

InChI Key InChIKey=URHATDOBWHTBOV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088401   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088401(2-(4-Methoxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoi...)
Affinity DataKi:  0.770nMAssay Description:Binding affinity towards cloned human alpha-1A adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088401(2-(4-Methoxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoi...)
Affinity DataKi:  51nMAssay Description:Binding affinity towards cloned human alpha-1D adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088401(2-(4-Methoxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoi...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity towards cloned human alpha-1B adrenergic receptor was determined using [125]-HEAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed