BDBM50088531 CHEMBL3576943::US10189805, Compound 19

SMILES N[C@@H](CCC(=O)NCc1ccccc1CS(=O)(=O)N1CCOCC1)C(O)=O

InChI Key InChIKey=DEWGVKOHGFRLOU-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088531   

TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50088531(CHEMBL3576943 | US10189805, Compound 19)
Affinity DataIC50:  6.77E+5nMAssay Description:The glutamine uptake assays in HEK293 cells were carried out in 96 well plates (CulturPlate-96, Perkin Elmer). Cells were plated at a density of 35,0...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50088531(CHEMBL3576943 | US10189805, Compound 19)
Affinity DataIC50:  6.77E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed