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BDBM50088625 (1R,2R,3R,4S,5R)-4-Amino-5-methoxy-cyclopentane-1,2,3-triol::(1R,2R,3R,4S,5R)-4-amino-5-methoxycyclopentane-1,2,3-triol::CHEMBL427643::Mannostatin analogue, 5

SMILES: CO[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O

InChI Key: InChIKey=NLCVJSNNNWJBCS-YDMGZANHSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Golgi alpha-mannosidase II


(Drosophila melanogaster (Fruit fly))
BDBM50088625
PNG
((1R,2R,3R,4S,5R)-4-Amino-5-methoxy-cyclopentane-1,...)
Show SMILES CO[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1
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PC cid
PC sid
PDB
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Article
PubMed
76n/an/an/an/an/an/an/an/a



University of Toronto



Assay Description
The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...


Chembiochem 10: 268-77 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)