BDBM50089193 4-Fluoro-N-(1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-benzenesulfonamide::CHEMBL310242

SMILES CC1(C)[C@H]2CCC(C)(C2)[C@H]1NS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=PBMVETGVYGTZMP-XPFLZZBLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089193   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50089193(4-Fluoro-N-(1,3,3-trimethyl-bicyclo[2.2.1]hept-2-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Abeta42 production by inhibiting Gamma-secretase proteolytic pathway in HEK293 cell stably transfected with a double mutant form of hum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed